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REXEED-A


Gamma sterilized wet-type dialyzer

Best biocompatible membrane

Higher clearance of small molecules and low molecular weight proteins

Large membrane surface area 2.5m2 available

Clearance(in vitro)

  REXEED-13A REXEED-15A
Blood Flow (mL/min) 200 300 400 200 300 400
Clearances (mL/min)1) Urea 194 264 306 196 272 317
Creatinine 188 247 284 191 255 296
Phosphate 180 227 259 185 238 272
Vitamin B12 133 155 165 142 168 179
Inulin (Qb=200mL/min) 78 87
KoA (Urea)(mL/min)2) 1027 1190
KUF (mL/hr/mmHg (mL//hr/kPa))3) 66 (495) 72 (540)
Effectives Surface Area (m2) 1.3 1.5
Sieving Coefficient4) Inulin 1.0
β2-microglobulin 0.8
Myoglobin 0.4
Albumin 0.001
  REXEED-18A REXEED-21A
Blood Flow (mL/min) 200 300 400 200 300 400
Clearances (mL/min)1) Urea 198 280 330 199 284 340
Creatinine 194 265 309 195 272 317
Phosphate 190 250 289 192 257 299
Vitamin B12 152 183 197 160 194 212
Inulin (Qb=200mL/min) 92 102
KoA (Urea)(mL/min)2) 1415 1569
KUF (mL/hr/mmHg (mL//hr/kPa))3) 81 (608) 90 (675)
Effectives Surface Area (m2) 1.8 2.1
Sieving Coefficient4) Inulin 1.0
β2-microglobulin 0.8
Myoglobin 0.4
Albumin 0.001
  REXEED-25A
Blood Flow (mL/min) 200 300 400
Clearances (mL/min)1) Urea 199 287 350
Creatinine 196 280 330
Phosphate 194 260 303
Vitamin B12 163 199 225
Inulin (Qb=200mL/min) 117
KoA (Urea)(mL/min)2) 1714
KUF (mL/hr/mmHg (mL//hr/kPa))3) 102 (773)
Effectives Surface Area (m2) 2.5
Sieving Coefficient4) Inulin 1.0
β2-microglobulin 0.8
Myoglobin 0.4
Albumin 0.001

Conditions:
1) Clearances: Qd=500mL/min, Qf=0mL/min
2) KoA: Qb=300mL/min, Qd=500mL/min, Qf=0mL/min
3) KUF: bovine blood, TP=60±5g/L, Hct=32±2%, Qb=300mL/min
4) Sieving Coefficient: bovine plasma, TP=60±5g/L
ISO 8637:2004

Lineup

REXEED-13A
REXEED-18A
REXEED-25A

REXEED-15A
REXEED-21A

 

 

 

REXEED-A specifications

Specifications for REXEED-13A, REXEED-15A, REXEED-18A, REXEED-21A, REXEED-25A

  REXEED-13A REXEED-15A
Membrane REXBRANE™ (Asahi Polysulfone)
Internal Diameter of Hollow Fiber (μm) 185
Wall Thickness of Hollow Fiber (μm) 45
Priming Volume (mL) 76 86
Maximum TMP (mmHg (kPa)) 500 (66)
Maximum Blood Flow (mL/min) 500
Maximum Dialysate Flow (mL/min) 800
Dimensions (mm[L] x mm[D]) 334 x 38 334 x 41
Weight (g) 412 463
Sterilization Gamma-Ray
  REXEED-18A REXEED-21A
Membrane REXBRANE™ (Asahi Polysulfone)
Internal Diameter of Hollow Fiber (μm) 185
Wall Thickness of Hollow Fiber (μm) 45
Priming Volume (mL) 103 117
Maximum TMP (mmHg (kPa)) 500 (66)
Maximum Blood Flow (mL/min) 500
Maximum Dialysate Flow (mL/min) 800
Dimensions (mm[L] x mm[D]) 334 x 43 334 x 47
Weight (g) 520 604
Sterilization Gamma-Ray
  REXEED-25A
Membrane REXBRANE™ (Asahi Polysulfone)
Internal Diameter of Hollow Fiber (μm) 185
Wall Thickness of Hollow Fiber (μm) 45
Priming Volume (mL) 137
Maximum TMP (mmHg (kPa)) 500 (66)
Maximum Blood Flow (mL/min) 500
Maximum Dialysate Flow (mL/min) 800
Dimensions (mm[L] x mm[D]) 334 x 50
Weight (g) 675
Sterilization Gamma-Ray

Note: High permeability devices. Use only with ultrafiltration controlling equipment. ISO 8637:2004

Brendolan et al.
Dialytic performance evaluation of Rexeed™: A new polysulfone-based dialyzer with improved flow distributions.
THE INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS Vol. 28, no. 10, pp. 966-975, 2005
Nakamura et al.
Performance Evaluation of REXEED-15A.
Jpn. J. High Performance Membrane '05, Kidney and Dialysis, Suppl., 59: 145-149, 2005
Taguchi et al.
Effects of differences in dialyzers and anti-coagulant dosage on blood activation.
Jpn. J. High Performance Membrane '06, Kidney and Dialysis, Suppl., 61:206-209, 2006
Osawa et al.
The Characteristics of Dialyzers When Used for High-volume Pre-dilution On-line Hemodiafiltration.
Jpn. J. High Performance Membrane '08, Kidney and Dialysis, Suppl., 65:133-135, 2008
James B.Post, MD.
Thrombocytopenia Associated With Use of a Biocompatible Hemodialysis Membrane: A Case Report.
American Journal of Kidney Diseases, Vol 55, No 6 (June), e25-e28, 2010
Hoshiyama et al.
A study of dialysis conditions in patients with high body weight.
Jpn. J. High Performance Membrane '05, Kidney and Dialysis, Suppl., 59:39-43, 2005
Abe et al.
Clinical evaluation of plasma insulin and C-peptide levels with 3 different high-flux dialyzers in diabetic patients on hemodialysis.
The international JOURNAL OF ARTIFICIAL ORGANS Vol.31, No. 10, pp. 898-904, 2008