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ACF CUREFLO


Features

Features of CUREFLO

Asahi's high flux polysulfone membrane specially developed for CRRT with:

High permeability and sharp cut-off curve
Superior biocompatibility
Low albumin loss
Long filter life

Application of CUREFLO

Cureflo is intended for patients with renal failure who also suffer from severe complications, such as multiple organ failure or cardiac and circulatory problems, including cardiac insufficiency and edema, who are not adequately treated by intermittent dialysis therapy. Cureflo is used to correct and purify body fluid through continuous hemofiltration (normally in excess of 10 hrs.).

Performances

High permeability and sharp cut-off curve

Microporous gradient structure (dense and homogenous inside surface and porous outside area) provides "High permeability" and "Sharp cut-off" features.

In-house data: Product: ACF-110W
Bovine blood, Ht=35%, TP=6.5g/dL, QB=100mL/min, Qf=10mL/min, n=1

Superior biocompatibility

The change of WBC, C3a and granulocyte elastase is very small during treatment.

Clinical data Patient: n=6

Low albumin loss

In-house data
Bovine blood, Ht=35%, TP=6.5g/dL, QB=100mL/min, Qf=10mL/min, 24 hrs circulation

Long filter life

In-house data
Bovine blood, Ht=35%, TP=6.5g/dL, QB=200mL/min, Qf=30mL/min, n=2, 30 hrs circulation


Specifications

CUREFLO specifications

Specification ACF-130W ACF-180W
Hollow Fiber Material Polysulfone
Inside Diameter 200 μm
Wall Thickness 45 μm
Effective Surface Area 1.3 m2 1.8 m2
Priming Volume 80 mL 108 mL
Max. TMP 66 kPa (500 mmHg)
Sterilization Gamma-Ray
Specification ACF-110W
Hollow Fiber Material Polysulfone
Inside Diameter 200 μm
Wall Thickness 45 μm
Effective Surface Area 1.1 m2
Priming Volume 66 mL
Max. TMP 66 kPa (500 mmHg)
Sterilization Gamma-Ray

Applications

Circuit diagram

Ultrafiltration

In-house data
Bovine blood, Ht=32%, TP=6.0g/dL
In-house data: Product: ACF-110W
Bovine blood, Ht=35%, TP=6.5g/dL, QB=100mL/min, Qf=10mL/min, n=1


Featured References

Evaluation of a new polysulfone hemofilter for continuous renal replacement therapy.
Blood Purif. 32:133-8, 2011.
  • Floris et al.

References

  • Floris et al.
  • Evaluation of a new polysulfone hemofilter for continuous renal replacement therapy.
Blood Purif. 32:133-8, 2011.